Bidirectional promoters generate pervasive transcription in yeast
نویسندگان
چکیده
منابع مشابه
Transcription factor binding and modified histones in human bidirectional promoters.
Bidirectional promoters have received considerable attention because of their ability to regulate two downstream genes (divergent genes). They are also highly abundant, directing the transcription of approximately 11% of genes in the human genome. We categorized the presence of DNA sequence motifs, binding of transcription factors, and modified histones as overrepresented, shared, or underrepre...
متن کاملPervasive antisense transcription is evolutionarily conserved in budding yeast.
Antisense transcription, or transcription on the opposite strand of the same genomic locus as another transcript, has been observed in many organisms, including yeast. Several antisense transcripts are known to be conserved across various species of yeast, and a few antisense transcripts are associated with functional regulation of the sense transcript. We detect antisense transcription from ap...
متن کاملAnalysis of bidirectional promoters in vertebrates
_____________________________________________________________________ 3 Acknowledgements ____________________________________________________________ 4
متن کاملDissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters☆
Brain-derived neurotrophic factor (BDNF), a member of the nerve growth factor family of neurotrophins, has central roles in the development, physiology, and pathology of the nervous system. We have elucidated the structure of the human BDNF gene, identified alternative transcripts, and studied their expression in adult human tissues and brain regions. In addition, the transcription initiation s...
متن کاملFunctional analysis of rice bidirectional promoters
.................................................................................................................................. 11 Literature review .................................................................................................................... 12 CHAPTER 1: .....................................................................................................................
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 2009
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature07728